Journal: The Journal of Dermatology
Article Title: Combination Effects of Clindamycin and Benzoyl Peroxide Against Cutibacterium acnes
doi: 10.1111/1346-8138.70170
Figure Lengend Snippet: Frequency of occurrence of clindamycin‐resistant mutant in Cutibacterium acnes . Standard susceptible strains of C. acnes (ATCC 6919 and ATCC 11828) were inoculated onto agar plates containing clindamycin alone or clindamycin/benzoyl peroxide and cultured for 48 h. Colony‐forming units (CFU)/mL were counted to evaluate the frequency of resistance emergence. Data represent the mean ± standard deviation of three independent experiments. Statistical analysis was performed using Student's t ‐test, with * p < 0.05 considered significant.
Article Snippet: The frequency of clindamycin‐resistant mutants ranged from 4.9 × 10 −8 to 1.5 × 10 −7 CFU/mL for ATCC 6919 and from 6.0 × 10 −8 to 1.2 × 10 −7 CFU/mL for ATCC 11828 in the clindamycin alone group.
Techniques: Mutagenesis, Cell Culture, Standard Deviation